Discovery of the lysosome In 1949, de Duve, a scientist at the Institute of Cytopathology in Brussels, Belgium, homogenized rat liver tissue and isolated various organelles with a view to identifying those related to enzymes of glucose metabolism, and hypothesized that a new organelle existed in
Interleukins are a very important genetic group of cytokines. As of 2022, 40 members have been recognized; they play an important role in a series of processes such as the maturation, activation, proliferation and immune regulation of immune cells.In addition, interleukins are involved in a variety
The full name of VEGFA is vascular endothelial growth factor A. Angiogenesis stimulators include a class of cytokines called “antigenic growth factors”, which play a role in stimulating cardiovascular formation. Some angiogenesis-stimulating factors have been found, such as platelet-derived
In 2012, the team of Brent R. Stockwell at Columbia University first proposed a new type of programmed cell death called ferroptosis. Since then, the upsurge of ferroptosis-related research has been increasing year by year. In 2012, the team of Brent R. Stockwell at Columbia University first propose
Pyroptosis Definition and Characteristics Pyroptosis is a new mode of programmed cell death that relies on Gasdermin family proteins for the formation of plasma membrane pores and regulated cell death, often but not always accomplished by activation of inflammatory caspases. Its mor
Mechanisms of ferroptosis in the treatment of liver fibrosis A new type of programmed cell death called ferroptosis was first proposed by Brent R. Stockwell's group at Columbia University in 2012. Since then, the research on ferroptosis has been increasing year by year. This issue of ELK 
Regulation of the p75 neurotrophin receptor attenuates neuroinflammation and stimulates hippocampal neurogenesis in experimental Streptococcus pneumoniae meningitis(Article Analysis) Subject: Regulation of the p75 neurotrophin receptor attenuates neuroinflammation and stimulates hippoca
Tissue homogenate definition: A thick liquid in the form of a solid-liquid mixture formed by disintegrating the differentiated cell population by physical-mechanical means or other methods, releasing the cell contents, and forming a solid-liquid mixture with the cell debris. 1. Take an appropriat