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GCS-β-2 rabbit pAb
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ES5691
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50 µL $148.00
100 µL $248.00
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Overview

Product name: GCS-β-2 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: GUCY1B2; Guanylate cyclase soluble subunit beta-2; GCS-beta-2
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human GCS-beta-2. AA range:53-102
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 70kD
GeneID: 2974
Human Swiss-Prot No: O75343
Cellular localization: Cytoplasm.
Background: Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.