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CYP2R1 rabbit pAb
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ES4681
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50 µL $148.00
100 µL $248.00
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Overview

Product name: CYP2R1 rabbit pAb
Reactivity: Human;Mouse;Monkey
Alternative Names: CYP2R1; Vitamin D 25-hydroxylase; Cytochrome P450 2R1
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CYP2R1. AA range:251-300
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 52kD
GeneID: 120227
Human Swiss-Prot No: Q6VVX0
Cellular localization: Endoplasmic reticulum membrane ; Peripheral membrane protein. Microsome membrane ; Peripheral membrane protein.
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency. [provided by RefSeq, Jul 2008],