| Product name: |
Exo1 rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
EXO1; EXOI; HEX1; Exonuclease 1; hExo1; Exonuclease I; hExoI |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human EXO1. AA range:61-110 |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
94kD |
| GeneID: |
9156 |
| Human Swiss-Prot No: |
Q9UQ84 |
| Cellular localization: |
Nucleus . Colocalizes with PCNA to discrete nuclear foci in S-phase. |
| Background: |
This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008], |
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