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BRCAA1 rabbit pAb
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ES1789
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50 µL $148.00
100 µL $248.00
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Overview

Product name: BRCAA1 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: ARID4B; BRCAA1; RBBP1L1; RBP1L1; SAP180; AT-rich interactive domain-containing protein 4B; ARID domain-containing protein 4B; 180 kDa Sin3-associated polypeptide; Sin3-associated polypeptide p180; Breast cancer-associated antigen BRCAA1; Hi
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human BRCAA1. AA range:761-810
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 148kD
GeneID: 51742
Human Swiss-Prot No: Q4LE39
Cellular localization: Nucleus . Cytoplasm . Cytoplasmic in breast cancer cells. .
Background: This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008],