Research Area

Epigenetics
source:ELKdate:2024-01-31views:1154

Epigenetics 

Epigenetics is a sub-discipline of genetics that studies heritable changes in gene expression without changes in the nucleotide sequence of genes. Its research includes two main categories, one for the regulation of selective transcriptional expression of genes, with DNA methylation, gene imprinting, covalent modification of histones, and chromatin remodeling; and the other for the post-transcriptional regulation of genes, including non-coding RNAs in the genome, micro RNAs, antisense RNAs, introns and riboswitches. With these techniques, researchers can map the panorama of methylation and chromatin modifications at the genomic level, which in turn can reveal epigenetic differences between different cell types, tissue types, developmental stages, and disease states.
 

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