Products

IL-27A rabbit pAb
One-click to copy product information
ES8732
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: IL-27A rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: Interleukin-27 subunit alpha (IL-27 subunit alpha;IL-27-A;IL27-A;p28)
Source: Rabbit
Dilutions: IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 1-50
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID: 246778
Human Swiss-Prot No: Q8NEV9
Cellular localization: Secreted . Does not seem to be secreted without coexpression of EBI3.
Background: The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq, Jul 2008],