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DCT rabbit pAb
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ES8595
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50 µL $148.00
100 µL $248.00
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Overview

Product name: DCT rabbit pAb
Reactivity: Human;Rat;Mouse
Alternative Names: L-dopachrome tautomerase (DCT;DT;EC 5.3.3.12;L-dopachrome Delta-isomerase;Tyrosinase-related protein 2;TRP-2;TRP2)
Source: Rabbit
Dilutions: WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 232-304
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 59kD
GeneID: 1638
Human Swiss-Prot No: P40126
Cellular localization: Melanosome membrane ; Single-pass type I membrane protein . Melanosome . Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38. .
Background: catalytic activity:L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.,cofactor:Binds 2 zinc ions per subunit.,function:Involved in regulating eumelanin and phaeomelanin levels.,pathway:Pigment biosynthesis; melanin biosynthesis.,similarity:Belongs to the tyrosinase family.,subunit:Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex.,