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TyrRS rabbit pAb
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ES8516
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50 µL $148.00
100 µL $248.00
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Overview

Product name: TyrRS rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)
Source: Rabbit
Dilutions: WB 1:500-2000,IHC 1:50-300 ELISA 1:10000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human YARS. AA range:451-500
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 60kD
GeneID: 8565
Human Swiss-Prot No: P54577
Cellular localization: Cytoplasm .
Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. [provided by RefSeq, Jul 2008],