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MSH2 rabbit pAb
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ES6281
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50 µL $148.00
100 µL $248.00
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Overview

Product name: MSH2 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: MSH2; DNA mismatch repair protein Msh2; hMSH2; MutS protein homolog 2
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human MSH2. AA range:541-590
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 100kD
GeneID: 4436
Human Swiss-Prot No: P43246
Cellular localization: Nucleus . Chromosome .
Background: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],