Products

Max (phospho Ser2) rabbit pAb
One-click to copy product information
ES6194
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: Max (phospho Ser2) rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: MAX; BHLHD4; Protein max; Class D basic helix-loop-helix protein 4; bHLHd4; Myc-associated factor X
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human MAX around the phosphorylation site of Ser2. AA range:1-50
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 18kD
GeneID: 4149
Human Swiss-Prot No: P61244
Cellular localization: Nucleus. Cell projection, dendrite .
Background: The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],