Arrestin-C rabbit pAb

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Arrestin-C rabbit pAb

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ES6145

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	Arrestin-C rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	ARR3; ARRX; CAR; Arrestin-C; Cone arrestin; C-arrestin; cArr; Retinal cone arrestin-3; X-arrestin
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human ARRC. AA range:339-388
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	40kD
GeneID:	407
Human Swiss-Prot No:	P36575
Cellular localization:	Photoreceptor inner segment . Cell projection, cilium, photoreceptor outer segment .
Background:	The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016],

Western blot analysis of lysates from LOVO cells, using ARRC Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).