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NDUFS7 rabbit pAb
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ES5989
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50 µL $148.00
100 µL $248.00
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Overview

Product name: NDUFS7 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: NDUFS7; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7; mitochondrial; Complex I-20kD; CI-20kD; NADH-ubiquinone oxidoreductase 20 kDa subunit; PSST subunit
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human NDUFS7. AA range:164-213
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 24kD
GeneID: 374291
Human Swiss-Prot No: O75251
Cellular localization: Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .
Background: This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions. [provided by RefSeq, Jul 2008],