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IRAK-1 (phospho Ser376) rabbit pAb
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ES5916
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50 µL $148.00
100 µL $248.00
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Overview

Product name: IRAK-1 (phospho Ser376) rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: IRAK1; IRAK; Interleukin-1 receptor-associated kinase 1; IRAK-1
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human IRAK1 around the phosphorylation site of Ser376. AA range:342-391
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 77kD
GeneID: 3654
Human Swiss-Prot No: P51617
Cellular localization: Cytoplasm . Nucleus . Lipid droplet . Translocates to the nucleus when sumoylated. RSAD2/viperin recruits it to the lipid droplet (By similarity). .
Background: This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],