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IL-11 rabbit pAb
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ES5892
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50 µL $148.00
100 µL $248.00
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Overview

Product name: IL-11 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: IL11; Interleukin-11; IL-11; Adipogenesis inhibitory factor; AGIF; Oprelvekin
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human IL-11. AA range:27-76
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 21kD
GeneID: 3589
Human Swiss-Prot No: P20809
Cellular localization: Secreted .
Background: The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012],