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IL-9R (phospho Ser519) rabbit pAb
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ES5889
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50 µL $148.00
100 µL $248.00
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Overview

Product name: IL-9R (phospho Ser519) rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: IL9R; Interleukin-9 receptor; IL-9 receptor; IL-9R; CD antigen CD129
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human IL-9R around the phosphorylation site of Ser519. AA range:472-521
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 57kD
GeneID: 3581
Human Swiss-Prot No: Q01113
Cellular localization: Cell membrane; Single-pass type I membrane protein. Secreted.
Background: The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008],