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IL-4 rabbit pAb
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ES5878
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50 µL $148.00
100 µL $248.00
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OverviewPublications(1)

Product name: IL-4 rabbit pAb
Reactivity: Human;Mouse
Alternative Names: IL4; Interleukin-4; IL-4; B-cell stimulatory factor 1; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra
Source: Rabbit
Dilutions: WB 1:500-2000;Flow Cyt 1:50-200;ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from the C-terminal region of human IL-4.
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 18kD
GeneID: 3565
Human Swiss-Prot No: P05112
Cellular localization: Secreted.
Background: The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],