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ALS rabbit pAb
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ES5855
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50 µL $148.00
100 µL $248.00
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Overview

Product name: ALS rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: IGFALS; ALS; Insulin-like growth factor-binding protein complex acid labile subunit; ALS
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human IGFALS. AA range:303-352
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 66kD
GeneID: 3483
Human Swiss-Prot No: P35858
Cellular localization: Secreted, extracellular space.
Background: The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],