Synaptotagmin X rabbit pAb

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Synaptotagmin X rabbit pAb

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ES5822

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	Synaptotagmin X rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	SYT10; Synaptotagmin-10; Synaptotagmin X; SytX
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300
Immunogen:	Synthesized peptide derived from Synaptotagmin X . at AA range: 380-460
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	55kD
GeneID:	341359
Human Swiss-Prot No:	Q6XYQ8
Cellular localization:	Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein . Localizes to neuronal vesicles containing IGF1 that are not enriched at synapses. Does not colocalize with synaptic vesicles or with the Golgi apparatus. .
Background:	cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers.,tissue specificity:Expressed only in pancreas, lung and kidney.,

Western Blot analysis of 293 cells using Synaptotagmin X Polyclonal Antibody
Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).