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HoxD8 rabbit pAb
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ES5766
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50 µL $148.00
100 µL $248.00
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Overview

Product name: HoxD8 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: HOXD8; HOX4E; Homeobox protein Hox-D8; Homeobox protein Hox-4E; Homeobox protein Hox-5.4
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human HOXD8. AA range:241-290
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 32kD
GeneID: 3234
Human Swiss-Prot No: P13378
Cellular localization: Nucleus.
Background: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010],