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HoxA5 rabbit pAb
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ES5760
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50 µL $148.00
100 µL $248.00
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Overview

Product name: HoxA5 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: HOXA5; HOX1C; Homeobox protein Hox-A5; Homeobox protein Hox-1C
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from the N-terminal region of human HoxA5.
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 40kD
GeneID: 3202
Human Swiss-Prot No: P20719
Cellular localization: Nucleus.
Background: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. [provided by RefSeq, Jul 2008],