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Cadherin-20 rabbit pAb
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ES5578
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Cadherin-20 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: CDH20; CDH7L3; Cadherin-20
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CDH20. AA range:111-160
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 89kD
GeneID: 28316
Human Swiss-Prot No: Q9HBT6
Cellular localization: Cell membrane; Single-pass type I membrane protein.
Background: This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008],