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Gγ 5 rabbit pAb
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ES5569
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Gγ 5 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: GNG5; GNGT5; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
Source: Rabbit
Dilutions: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human GNG5. AA range:10-59
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 7kD
GeneID: 2787
Human Swiss-Prot No: P63218
Cellular localization: Cell membrane ; Lipid-anchor ; Cytoplasmic side .
Background: G protein subunit gamma 5(GNG5) Homo sapiens G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010],