Products

Gα t2 rabbit pAb
One-click to copy product information
ES5568
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: Gα t2 rabbit pAb
Reactivity: Human;Mouse
Alternative Names: GNAT2; GNATC; Guanine nucleotide-binding protein G(t) subunit alpha-2; Transducin alpha-2 chain
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human GNAT2. AA range:1-50
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 40kD
GeneID: 2780
Human Swiss-Prot No: P19087
Cellular localization: Cell projection, cilium, photoreceptor outer segment . Photoreceptor inner segment . Localizes mainly in the outer segment in the dark-adapted state, whereas is translocated to the inner part of the photoreceptors in the light-adapted state. During dark-adapted conditions, in the presence of UNC119 mislocalizes from the outer segment to the inner part of rod photoreceptors which leads to decreased photoreceptor damage caused by light. .
Background: Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones. [provided by RefSeq, Jul 2008],