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AMPD3 rabbit pAb
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ES5545
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50 µL $148.00
100 µL $248.00
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Overview

Product name: AMPD3 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: AMPD3; AMP deaminase 3; AMP deaminase isoform E; Erythrocyte AMP deaminase
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from AMPD3 . at AA range: 280-360
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 89kD
GeneID: 272
Human Swiss-Prot No: Q01432
Cellular localization: cytosol,
Background: This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008],