Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen:
The antiserum was produced against synthesized peptide derived from human CD57. AA range:35-84
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Molecular Weight:
38kD
GeneID:
27087
Human Swiss-Prot No:
Q9P2W7
Cellular localization:
[Isoform 1]: Golgi apparatus membrane ; Single-pass type II membrane protein . Secreted .; [Isoform 2]: Golgi apparatus membrane ; Single-pass type II membrane protein . Endoplasmic reticulum membrane . Secreted .
Background:
The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008],