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AMPD1 rabbit pAb
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ES5526
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50 µL $148.00
100 µL $248.00
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Overview

Product name: AMPD1 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: AMPD1; AMP deaminase 1; AMP deaminase isoform M; Myoadenylate deaminase
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPD1. AA range:261-310
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 86kD
GeneID: 270
Human Swiss-Prot No: P23109
Cellular localization: cytosol,
Background: Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010],