Products

Somatotropin rabbit pAb
One-click to copy product information
ES5517
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: Somatotropin rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: GH1; Somatotropin; Growth hormone; GH; GH-N; Growth hormone 1; Pituitary growth hormone
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from the Internal region of human Somatotropin.
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 25kD
GeneID: 2688
Human Swiss-Prot No: P01241
Cellular localization: Secreted.
Background: The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq, Jul 2008],