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GDF-8 rabbit pAb
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ES5504
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50 µL $148.00
100 µL $248.00
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Overview

Product name: GDF-8 rabbit pAb
Reactivity: Human;Mouse
Alternative Names: MSTN; GDF8; Growth/differentiation factor 8; GDF-8; Myostatin
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human GDF-8. AA range:38-87
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 43kD
GeneID: 2660
Human Swiss-Prot No: O14793
Cellular localization: Secreted .
Background: myostatin(MSTN) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016],