SERGEF rabbit pAb

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SERGEF rabbit pAb

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ES5490

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	SERGEF rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	SERGEF; DELGEF; GNEFR; Secretion-regulating guanine nucleotide exchange factor; Deafness locus-associated putative guanine nucleotide exchange factor; DelGEF; Guanine nucleotide exchange factor-related protein
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen:	The antiserum was produced against synthesized peptide derived from human SERGEF. AA range:179-228
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	50kD
GeneID:	26297
Human Swiss-Prot No:	Q9UGK8
Cellular localization:	Cytoplasm . Nucleus .
Background:	function:Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 RCC1 repeats.,subunit:Interacts with SEC5. The interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP.,

Western blot analysis of SERGEF Antibody. The lane on the right is blocked with the SERGEF peptide.
Western blot analysis of the lysates from HT-29 cells using SERGEF antibody.
Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).