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AMY-1 rabbit pAb
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ES5489
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50 µL $148.00
100 µL $248.00
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Overview

Product name: AMY-1 rabbit pAb
Reactivity: Human;Mouse
Alternative Names: MYCBP; AMY1; C-Myc-binding protein; Associate of Myc 1; AMY-1
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from AMY-1 . at AA range: 30-110
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 12kD
GeneID: 26292
Human Swiss-Prot No: Q99417
Cellular localization: Cytoplasm. Nucleus. Mitochondrion. Translocates into the nucleus in the S phase of the cell cycle upon an increase of MYC expression. Found in the mitochondria when associated with AKAP1.
Background: The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. [provided by RefSeq, Nov 2011],