TIN2 rabbit pAb

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TIN2 rabbit pAb

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ES5486

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	TIN2 rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	TINF2; TIN2; TERF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human TINF2. AA range:71-120
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	53kD
GeneID:	26277
Human Swiss-Prot No:	Q9BSI4
Cellular localization:	Nucleus . Chromosome, telomere . Associated with telomeres.; [Isoform 1]: Nucleus matrix .
Background:	This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq, Mar 2010],

Western blot analysis of lysates from HUVEC cells, using TINF2 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from HeLa cells using TINF2 antibody.
Immunohistochemical analysis of paraffin-embedded human oophoroma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).