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MIP-T3 rabbit pAb
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ES5467
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50 µL $148.00
100 µL $248.00
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Overview

Product name: MIP-T3 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: TRAF3IP1; MIPT3; TRAF3-interacting protein 1; Interleukin-13 receptor alpha 1-binding protein 1; Microtubule-interacting protein associated with TRAF3; MIP-T3
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human MIPT3. AA range:221-270
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 78kD
GeneID: 26146
Human Swiss-Prot No: Q8TDR0
Cellular localization: Cytoplasm, cytoskeleton . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, cilium basal body . Microtubules (PubMed:12935900). In the cilium, it is observed at the ciliary base, ciliary transition zone and ciliary tip (PubMed:26487268). .
Background: function:Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules.,similarity:Belongs to the TRAF3IP1 family.,subcellular location:Microtubules.,subunit:Interacts with IL13RA1. Binds to microtubules, TRAF3 and DISC1.,tissue specificity:Ubiquitous.,