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T2R45 rabbit pAb
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ES5451
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50 µL $148.00
100 µL $248.00
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Overview

Product name: T2R45 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: TAS2R45; GPR59; Taste receptor type 2 member 45; T2R45; G-protein coupled receptor 59
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human TAS2R45. AA range:221-270
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 35kD
GeneID: 259291
Human Swiss-Prot No: P59539
Cellular localization: Membrane; Multi-pass membrane protein.
Background: function:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.,miscellaneous:Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.,