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Rad54B rabbit pAb
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ES5438
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Rad54B rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: RAD54B; DNA repair and recombination protein RAD54B; RAD54 homolog B
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human RAD54B. AA range:241-290
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 103kD
GeneID: 25788
Human Swiss-Prot No: Q9Y620
Cellular localization: Nucleus .
Background: The RAD54 homolog B encoded by RAD54B belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.