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V-ATPase C2 rabbit pAb
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ES5395
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50 µL $148.00
100 µL $248.00
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Overview

Product name: V-ATPase C2 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: ATP6V1C2; V-type proton ATPase subunit C 2; V-ATPase subunit C 2; Vacuolar proton pump subunit C 2
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human ATP6V1C2. AA range:121-170
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 48kD
GeneID: 245973
Human Swiss-Prot No: Q8NEY4
Cellular localization: vacuolar proton-transporting V-type ATPase, V1 domain,lysosomal membrane,cytosol,proton-transporting V-type ATPase, V1 domain,extracellular exosome,
Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms. [provided by RefSeq, Jul 2008],