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LDOC1 rabbit pAb
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ES5375
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Overview

Product name: LDOC1 rabbit pAb
Reactivity: Human;Mouse
Alternative Names: LDOC1; BCUR1; Protein LDOC1; Leucine zipper protein down-regulated in cancer cells
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human LDOC1. AA range:21-70
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 17kD
GeneID: 23641
Human Swiss-Prot No: O95751
Cellular localization: Nucleus .
Background: The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008],