Cdc42EP4 rabbit pAb

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Cdc42EP4 rabbit pAb

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ES5363

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	Cdc42EP4 rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	CDC42EP4; BORG4; CEP4; Cdc42 effector protein 4; Binder of Rho GTPases 4
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human BORG4. AA range:201-250
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	36kD
GeneID:	23580
Human Swiss-Prot No:	Q9H3Q1
Cellular localization:	Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Background:	The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008],

Western blot analysis of lysates from Jurkat cells, using BORG4 Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).