Raftlin rabbit pAb

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Raftlin rabbit pAb

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ES5314

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	Raftlin rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	RFTN1; KIAA0084; MIG2; Raftlin; Cell migration-inducing gene 2 protein; Raft-linking protein
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300
Immunogen:	The antiserum was produced against synthesized peptide derived from human RFTN1. AA range:432-481
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	65kD
GeneID:	23180
Human Swiss-Prot No:	Q14699
Cellular localization:	Cell membrane ; Lipid-anchor . Cytoplasm . Membrane raft . Endosome . Early endosome . Translocates from cytoplasm to cell membrane where it colocalizes with poly (I:C) and then moves to endosomes where it colocalizes with TLR3 (PubMed:21266579). Translocates from cytoplasm to cell membrane where it colocalizes with TLR4 and then together with TLR4 moves to endosomes, upon lipopolysaccharide stimulation (PubMed:27022195). .
Background:	function:May play a pivotal role in the formation and/or maintenance of lipid rafts. May regulate B-cell antigen receptor-mediated signaling.,similarity:Belongs to the raftlin family.,subcellular location:Associates with lipid rafts.,tissue specificity:Specifically expressed by B-cells (at protein level).,

Western Blot analysis of 3T3 cells using Raftlin Polyclonal Antibody
Western blot analysis of RFTN1 Antibody. The lane on the right is blocked with the RFTN1 peptide.
Western blot analysis of the lysates from RAW264.7cells using RFTN1 antibody.
Immunohistochemical analysis of paraffin-embedded human uterus. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).