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Ets-1 (phospho Ser251) rabbit pAb
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ES5180
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Ets-1 (phospho Ser251) rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: ETS1; EWSR2; Protein C-ets-1; p54
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Ets-1 (phospho Ser251)
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 50kD
GeneID: 2113
Human Swiss-Prot No: P14921
Cellular localization: Cytoplasm . Nucleus . Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27. .
Background: This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011],