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Elk-1 (phospho Ser389) rabbit pAb
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ES5094
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Elk-1 (phospho Ser389) rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: ELK1; ETS domain-containing protein Elk-1
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Elk1 around the phosphorylation site of Ser389. AA range:356-405
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 48kD
GeneID: 2002
Human Swiss-Prot No: P19419
Cellular localization: Nucleus.
Background: This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012],