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ECM1 rabbit pAb
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ES5039
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50 µL $148.00
100 µL $248.00
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Overview

Product name: ECM1 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: ECM1; Extracellular matrix protein 1; Secretory component p85
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from the N-terminal region of human ECM1.
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 61kD
GeneID: 1893
Human Swiss-Prot No: Q16610
Cellular localization: Secreted, extracellular space, extracellular matrix.
Background: This gene encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Feb 2011],