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Dsg2 rabbit pAb
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ES5028
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Dsg2 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: DSG2; CDHF5; Desmoglein-2; Cadherin family member 5; HDGC
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human DSG2. AA range:401-450
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 140kD
GeneID: 1829
Human Swiss-Prot No: Q14126
Cellular localization: Cell membrane ; Single-pass type I membrane protein. Cell junction, desmosome.
Background: This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016],