DOCK 2 rabbit pAb

Products

DOCK 2 rabbit pAb

One-click to copy product information

ES5016

Size：	Price：
50 µL	$148.00
100 µL	$248.00

Manual Send email to us

Overview

Product name:	DOCK 2 rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	DOCK2; KIAA0209; Dedicator of cytokinesis protein 2
Source:	Rabbit
Dilutions:	WB 1:500-2000 ,Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:	Synthesized peptide derived from the Internal region of human DOCK 2.
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Molecular Weight:	212kD
GeneID:	1794
Human Swiss-Prot No:	Q92608
Cellular localization:	Endomembrane system ; Peripheral membrane protein . Cytoplasm, cytoskeleton . Colocalizes with F-actin.
Background:	The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. [provided by RefSeq, Oct 2016],

Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).