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Cleaved-Aggrecan (D369) rabbit pAb
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ES5012
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Cleaved-Aggrecan (D369) rabbit pAb
Reactivity: Human;Rat
Alternative Names: ACAN; AGC1; CSPG1; MSK16; Aggrecan core protein; Cartilage-specific proteoglycan core protein; CSPCP; Chondroitin sulfate proteoglycan core protein 1; Chondroitin sulfate proteoglycan 1
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Aggrecan. AA range:320-369
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 44kD
GeneID: 176
Human Swiss-Prot No: P16112
Cellular localization: Secreted, extracellular space, extracellular matrix .
Background: This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008],