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Dynamin I (phospho Ser778) rabbit pAb
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ES5009
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Dynamin I (phospho Ser778) rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: DNM1; DNM; Dynamin-1
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human DYN1 around the phosphorylation site of Ser778. AA range:751-800
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 100kD
GeneID: 1759
Human Swiss-Prot No: Q05193
Cellular localization: Cytoplasm . Cytoplasm, cytoskeleton . Microtubule-associated.
Background: dynamin 1(DNM1) Homo sapiens This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],