Products

ZnT-8 rabbit pAb
One-click to copy product information
ES4993
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: ZnT-8 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: SLC30A8; ZNT8; Zinc transporter 8; ZnT-8; Solute carrier family 30 member 8
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human SLC30A8. AA range:171-220
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 41kD
GeneID: 169026
Human Swiss-Prot No: Q8IWU4
Cellular localization: Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, secretory vesicle membrane ; Multi-pass membrane protein . Associated with insulin and glucagon secretory granules. .
Background: The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010],