Nesprin-3 rabbit pAb

Products

Nesprin-3 rabbit pAb

One-click to copy product information

ES4963

Size：	Price：
50 µL	$148.00
100 µL	$248.00

Manual Send email to us

Overview

Product name:	Nesprin-3 rabbit pAb
Reactivity:	Human;Mouse
Alternative Names:	SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human C14orf49. AA range:169-218
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	115kD
GeneID:	161176
Human Swiss-Prot No:	Q6ZMZ3
Cellular localization:	Nucleus outer membrane ; Single-pass type IV membrane protein . Nucleus envelope . Rough endoplasmic reticulum .
Background:	function:Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which theters the nucleus to the cytoskeleton by binding PLEC1/Plectin which can associate with the intermediate filament system.,similarity:Belongs to the nesprin family.,similarity:Contains 1 KASH domain.,similarity:Contains 2 spectrin repeats.,subcellular location:Located at the rough reticulum endoplasmic (RER) in some cells.,subunit:Interacts with actin-binding domain of PLEC1/plectin.,

Western Blot analysis of Jurkat cells using Nesprin-3 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Western blot analysis of lysates from Jurkat cells, using C14orf49 Antibody. The lane on the right is blocked with the synthesized peptide.