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CYP3A7 rabbit pAb
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ES4928
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50 µL $148.00
100 µL $248.00
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Overview

Product name: CYP3A7 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: CYP3A7; Cytochrome P450 3A7; CYPIIIA7; Cytochrome P450-HFLA
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Cytochrome P450 3A7. AA range:231-280
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 50kD
GeneID: 1551
Human Swiss-Prot No: P24462
Cellular localization: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane ; Peripheral membrane protein.
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene and is represented by GeneID:100861540. [provided by RefSeq, Jan 2015],