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NBPF4 rabbit pAb
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ES4881
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50 µL $148.00
100 µL $248.00
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Overview

Product name: NBPF4 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: NBPF4; Neuroblastoma breakpoint family member 4
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human NBPF4. AA range:48-97
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 14kD
GeneID: 148545
Human Swiss-Prot No: Q96M43
Cellular localization: Cytoplasm .
Background: neuroblastoma breakpoint family member 4(NBPF4) Homo sapiens This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene fam